Myocardial Infarction-
- Untreated angina leads to myocardial infacrtion.
- Many early deaths are due to ventricular fibrillation or cardiac arrest.
- C/f-Pain,Dyspnoea,Vomiting,Nausea,perspiration.
- Nausea and vomitting during the attack can be due to sympathetic stimulation.
- Tachycardia(due to sympathetic stimulation),Cold extremities,Hypotension.
- Investigations-
- ECG- In initial hours there is ST segment elevation and latter followed by deepening of Q wave followed by T wave inversion.
- Changes in plasma enzyme levels of Creatinine kinase(CK),Aspartate dehydrogenase(ADH),Lactic acid dehydrogenase.CK starts appearing into blood after 4-6 hrs of infarction and reaches its peak after 12 hours of infarction and Vanishes after 2-3 days of infarction.LDH start to appear after 12 hours of attack and reach its maximum after 2-3 days of attack.
- X ray-cardiomegaly with pulmonary congestion
- Echocardiography
- Drug regime-Oxygen therapy,I.V Morphine(10mg),Streptokinase/Alteplase, Anti platelet drugs(aspirin and clopodigrel),Beta Blockers,TNG
Regular drug regime includes Aspirin/clopodigrel or combination,ACE inhibitors,Beta blockers.
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